Naloxone recall due to particulate matter

The opioid overdose antidote Naloxone has been recalled by its maker, Hospira, ...

Posted: Jun 5, 2018 10:10 AM
Updated: Jun 5, 2018 10:10 AM

The opioid overdose antidote Naloxone has been recalled by its maker, Hospira, the US Food and Drug Administration said Monday.

The recall was prompted by the potential for "loose particulate matter on the syringe plunger" which could result in a range of adverse events. "In the event that impacted product is administered to a patient, the patient has a low likelihood of experiencing adverse events ranging from local irritation, allergic reactions, phlebitis, end-organ granuloma, tissue ischemia, pulmonary emboli, pulmonary dysfunction, pulmonary infarction, and toxicity."

Recall prompted by a concern over loose particulate matter

No instances of adverse events have been reported, according to the recall announcement. Anyone who experiences a related adverse event should report it to the FDA.

Naloxone Hydrochloride is sold for IV use, intramuscular use and subcutaneous use. The recall affects single use sterile cartridge units with lot numbers 72680LL and 76510LL in 0.4 mg/ml, 1 mL in, and 2.5 mL strengths. They were sent to wholesalers, distributors and hospitals in the United states, Puerto Rico and Guam between February 2017 and February 2018.

Hospira is asking distributors and retailers to discontinue using and distributing the recalled product and notify anyone who they have sent it to including stores, pharmacies and hospitals.

Naloxone used to only be available in hospitals but is now carried by many first responders, medical professionals and is available without a prescription in some places, all in response to the ongoing opioid epidemic.

When administered, Naloxone can quickly restore normal respiration to someone whose breathing has slowed or stopped due to opioids.

California Coronavirus Cases

Data is updated nightly.

Confirmed Cases: 506613

Reported Deaths: 9345
CountyConfirmedDeaths
Los Angeles1908574669
Riverside37011695
Orange36833649
San Bernardino32696417
San Diego29048561
Kern19882144
Fresno14439138
Alameda11484189
San Joaquin11483168
Santa Clara10321191
Sacramento9820133
Tulare9454178
Imperial9409220
Stanislaus8890104
Contra Costa7806121
Ventura734476
San Francisco672361
Santa Barbara616760
San Mateo5544119
Marin499470
Monterey479730
Kings438056
Merced428550
Solano361137
Sonoma294437
Madera194330
Placer191215
San Luis Obispo178315
Yolo151041
Santa Cruz11524
Butte9417
Napa8888
Sutter7686
El Dorado6371
Lassen6310
San Benito6224
Yuba4714
Shasta3699
Glenn3251
Colusa3234
Mendocino3129
Nevada2991
Tehama2341
Humboldt2334
Lake1951
Mono1421
Tuolumne1412
Amador1250
Calaveras1251
Del Norte880
Siskiyou730
Mariposa542
Inyo511
Plumas330
Trinity50
Alpine20
Modoc20
Sierra20
Unassigned00
Chico
Clear
77° wxIcon
Hi: 99° Lo: 67°
Feels Like: 78°
Oroville
Clear
78° wxIcon
Hi: 100° Lo: 68°
Feels Like: 79°
Paradise
Clear
77° wxIcon
Hi: 92° Lo: 68°
Feels Like: 78°
Chester
Clear
60° wxIcon
Hi: 82° Lo: 53°
Feels Like: 60°
Red Bluff
Clear
77° wxIcon
Hi: 100° Lo: 68°
Feels Like: 78°
Willows
Clear
77° wxIcon
Hi: 103° Lo: 65°
Feels Like: 78°
Monday will be hot but we will cool down in the middle of your week.
KHSL Severe
KHSL Radar
KHSL Temperatures

Community Events